We Provide  American Medical Standards World Class Doctors State of the Art Facilities Prestigious Medical Services Cutting Edge Technologies Patient Centeredness

5/2023- uptodate        Neurosurgeon at AIMIS Clinics

 

12/2019-uptodate       GESY Provider-Neurosurgeon

 

08/2019-2021             Attending Neurosurgeon, Henry Dunant medical center, Athens                            

 

07/2018-07/2019        Attending Neurosurgeon, department of Neurosurgery Central Clinic

                                   of Athens, Athens, Greece                 

                 

05/2016-06/2018        Attending neurosurgeon, department of Neurosurgery, imland Klinik

                                   Rendsburg, Germany              

 

7/2015-03/2016          Clinical Fellowship Skull base surgery

                                   Louisiana State University-Shreveport

                                   Chairman: Dr. A. Nanda

 

10/2013 - 06/2015      2 years Neuro-Oncology and Complex Spine (tumor based

                                   reconstruction) clinical Fellowship at University of                    

                                   South Florida/Moffitt Cancer Center

                                   Program Director: Dr. N. Tran

                                   Chief of Neurosurgery: Dr. F. Vrionis

• Main focus: surgical neuro-oncology (Brain and Spine)
• Strong emphasis on spinal instrumentation and degenerative disorders and reconstructive spine surgery
• Minimally invasive spinal procedures
• Pain management (RFA for tumors, ESI, spinal cord stimulator placement, kyphoplasty procedures)

 02/2006 - 03/2013     Resident Physician

                                   University of Erlangen-Nürnberg, Germany

                                   Department of Neurosurgery

                                   Chairman: Prof. Dr. M. Buchfelder

 

8/2008 - 06/2009        Research Fellowship

                                   Minimally Invasive Neurosurgery Lab

                                   Rainbow Babies and Children`s Hospital

                                   Case Western Reserve University, Ohio, USA

                                   Director: Prof. Dr. A. R. Cohen

 

12/2004 - 1//2006      Resident Physician

                                  Georg-August University of Göttingen, Germany

                                  Department of Neurosurgery,

                                  Chairman: Professor Dr. M. Buchfelder

 

6/2003 - 7/2004         Pre-Doctoral Research Position:  Athens Medical School:

                                  Department of Physiology, Cell Culture Laboratory,

                                  Subject: Culture of astrocytes, HPLC

 

1/1999 - 7/2003         Pre-Doctoral Research Position:  Athens Medical School:

                                  Department of Psychiatry, Laboratory of psychophysiology,

                                  Subject: Studied evoked related potentials in patients with

                                  traumatic brain injury, Parkinson’s disease, depression etc.

 

Professional courses

 

February 4-7, 2015 -             13^th Annual Masters Course in Skull Base Surgery, Tampa FL

 

November 14-15, 2014 -       Approaches for Brain Tumor and Vascular Neurosurgery, Hands-On Course, Tampa FL

 

July 19, 2014 -                      Radiofrequency-Targeted Vertebral Augmentation with the StabiliT System, Tampa, FL

 

March 1, 2014 -                    Complications in Complex Spine Surgery, Avoidance and Management, Medtronic, Tampa FL

 

February 21-22, 2014 -         Minimally Invasive Spinal Surgery and Navigation, Tampa FL

 

January 2014 -                      Kyphon Balloon Kyphoplasty, Tampa FL

 

January 27, 2012 -                Microscopic and endoscopic approaches to the skull base, Hands-On Course, IRCAD, Strasbourg,

 

May 27-29, 2010 -                 2^nd Baltic Sea 2010-International Hands-On Course on Full HD Endoscopic Neurosurgery, Greifswald,

 

February 4-5, 2010 -             Neurosurgical Management of Pituitary Tumors, Tuebingen,

 

January 10, 2010 -                Operative Techniques on degenerative lumbar spine, Hands-On Course, Munich,

 

 

2/2005 - 8/2007         Georg-August University of Göttingen, Germany. Department of

                                  Neurosurgery, Doctoral Thesis: Trigeminocardiac reflex in

                                  transsphenoidal surgery

                                               

1998-2004                 University of Athens Medical School, Greece, Medical Diploma

RESEARCH

 

2004 – 2006                Neuroendocrine Dysfunction Following a Traumatic Brain Injury

• In 82 patients admitted for TBI the cortico-, thyreo-, gonado-somatotropic as well as the posterior pituitary function were tested in days 0,3, and 7 after trauma. In some patients, there was also a dynamic pituitary test available. Our study showed that after TBI the hypopituitarism prevalence can be as high as 80%, and the persistent endocrine insufficiency is much less.

2004 – 2009                The Trigeminocardiac Reflex in Pituitary Surgery               

• In 40 patients who underwent transsphenoidal pituitary surgery the occurrence of the trigeminocardiac reflex was monitored intraoperatively. In 3 patients we had evidence of the reflex intraoperatively. Biomarkers and demographic data were used to identify predisposing factors for the occurrence of the reflex. In this study cerebral ischemia and possible correlation with the reflex (ischemic preconditioning) is discussed. 

 

 

ORAL PRESENTATIONS

 

September 2008 -      Filis A: The orbitozygomatic approach: one and two-piece. Case Western Reserve University, Dept. of Neurosurgery,

 

October 2008 -           Filis A: The subtemporal approach.. Case Western Reserve University, Dept. of Neurosurgery

 

November 2008 -     Filis A: Suboccipital approaches, surgery of the 4^th Ventricle (transvermian and telovelar approach). Case Western Reserve University, Dept. of Neurosurgery

 

December 2008 -       Filis A: Surgery for petroclival tumors, the petrosal approach. Case Western Reserve University, Dept. of Neurosurgery

 

January 2009 -           Filis A: The pterional approach, Surgery of Aneurysmas, transcavernous route. Case Wetern Reserve University, Dept. of Neurosurgery

 

March 2009 -         Filis A: The transcallosal and transcortical approach, surgery of the 3^rd  Ventricle (subchoroidal, transchoroidal,interforniceal) . Case Western Reserve University, Dept. of Neurosurgery, 2008

 

May 2009 -                 Filis A, Kahn F : Neurotrauma Lecture. Anatomy course, Case Western Reserve University, Dept. of Neurosurgery

 

May 2009 -                 Filis A, Khan F: Skull base surgery:pituitary tumor and acoustic schwanommas. Anatomy course. Case Western Reserve University, Dept. of  Neurosurgery

 

May 2009 -                 Filis A, Khan F: Microsurgical Approach to the posterior fossa. Anatomy Course. Case Western Reserve University, Dept. of Neurosurgery

 

May 2009 -               Filis A, Khan F: Anatomy of the posterior fossa. Anatomy course. Case Western Reserve University, Dept. of Neurosurgery

 

May 2009 -                 Filis A, Khan F: Vertebroplasty. Anatomy course. Case Western Reserve University, Dept. of Neurosurgery

 

May 2005 -                 Kleindienst, A. Filis, C. Bock, P. Valbuena, M. Buchfelder:  Neuroendocrine Dysfunction following a traumatic brain injury: a prospective longitudinal study. 57^th Meeting of the German Society of Neurosurgery,

 

August 2003 -             Papageorgiou C, Boviatsis E, Koujalis A, Kontopantelis E, Filis A (here misspelled as Phillis), Uzunoglou N, Sakkas D, Rabavilas A, Christodoulou G.  Assessment of P200 after moderate to severe brain injury. Journal of Psychosomatic Research. Volume 55, Number 2, August 2003, pp143-144

 

 

PEER REVIEWED BOOK CHAPTERS:

Schaller B, Filis A, Buchfelder M. (2008). Trigemino-Cardiac Reflex and Imaging The Promise of New Insights. In Schaller Bernhard (Ed.), Neuroscience imaging research trends (pp. 109-110). New York, NY. Nova Science Publishers.

Schaller B, Filis A, Buchfelder M. (2008). Expert Commentary: The Ying and yang of cardiac autonomic control in neurosurgery. In Océane M. Roux (Ed.), Brain Hypoxia-Ischemia Research (pp. 1-6). New York, NY. Nova Science Publisher.

 

A. Filis and F. Vrionis. Posterior cervical foraminotomy (accepted). In 2^nd edition of Handbook of Spine Surgery. Editors: Dr. Ali A. Baaj, Dr. Praveen V. Mummaneni, Dr. Juan S. Uribe, Dr. Alexander R. Vaccaro, and Dr. Mark S. Greenberg.

 

P. Alikhani, A. Filis and F. Vrionis. Spine Emergencies (submitted). In 2^nd edition of Handbook of Spine Surgery. Editors: Dr. Ali A. Baaj, Dr. Praveen V. Mummaneni, Dr. Juan S. Uribe, Dr. Alexander R. Vaccaro, and Dr. Mark S. Greenberg.

 

PUBLICATIONS

 

Vourla E, Filis A, Cornelius JF, Bostelmann R, Turowski B, Kalakoti P, Rubbert C, Suresh MP, Tortora A, Steiger HJ, Petridis AK. Natural History of De Novo Aneurysm Formation in Patients with Treated Aneurysmatic Subarachnoid Hemorrhage: A Ten-Year Follow-Up. World Neurosurg. 2018 Oct 12

 

Petridis AK, Filis A, Chasoglou E, Fischer I, Dibué-Adjei M, Bostelmann R, Steiger HJ, Turowski B, May R. Aneurysm wall enhancement in black blood MRI correlates with aneurysm size. Black blood MRI could serve as an objective criterion of aneurysm stability in near future. Clin Pract. 2018 Jul 27;8(3):1089

 

Fung C, Mavrakis E, Filis A, Fischer I, Suresh M, Tortora A, Cornelius JF, Bostelmann R, Gralla J, Beck J, Raabe A, Khan MO, Steiger HJ, Petridis AK. Anatomical evaluation of intracranial aneurysm rupture risk in patients with multiple aneurysms. Neurosurg Rev. 2018 Jun 30

 

Volkov AA, Filis AK, Vrionis FD. Surgical Treatment for Leptomeningeal Disease.

Cancer Control. 2017 Jan;24(1):47-53.

 

Filis AK, Aghayev K, Vrionis FD. Cerebrospinal Fluid and Hydrocephalus: Physiology, Diagnosis, and Treatment. Cancer Control. 2017 Jan;24(1):6-8.

 

Filis A, Kalakoti P, Connor DE, Nanda A. Elucidating the utility of neuro-navigation in reducing malposition rates in Ommaya reservoir placement: 23-year operative experience at the Louisiana State University. Neurol India. 2016 Nov-Dec;64(6):1195-1201

 

Filis AK, Robinson LA, Vrionis FD. Resection of the First Rib With Preservation of the T1 Nerve Root in Pancoast Tumors of the Lung. Cancer Control. 2016 Jul;23(3):295-301.

 

Filis AK, Aghayev K, Schaller B, Luksza J, Vrionis FD. Transdiscal mid- and upper thoracic vertebroplasty: first description of 2 exemplary cases. J Neurosurg Spine. 2016 Aug;25(2):193-7

 

Nanda A, Filis A, Kalakoti P. Mythological and Prehistorical Origins of Neurosurgery.

World Neurosurg. 2016 May;89:568-73. doi: 10.1016/j.wneu.2016.02.068. Review.

 

Filis A, Kalakoti P, Nanda A. Symptomatic ecchordosis physaliphora mimicking as an intracranial arachnoid cyst. J Clin Neurosci. 2016 Jun;28:171-4.

 

Chowdhury T, Nöthen C, Filis A, Sandu N, Buchfelder M, Schaller B. Functional Outcome Changes in Surgery for Pituitary Adenomas After Intraoperative Occurrence of the Trigeminocardiac Reflex: First Description in a Retrospective Observational Study.

Medicine (Baltimore). 2015 Sep;94(37):e1463

 

Doulgeris JJ, Gonzalez-Blohm SA, Filis AK, Shea TM, Aghayev K, Vrionis FD.

Robotics in Neurosurgery: Evolution, Current Challenges, and Compromises.

Cancer Control. 2015 Jul;22(3):352-9. Review.

 

Papanastassiou ID, Filis A, Gerochristou MA, Vrionis FD. Controversial issues in kyphoplasty and vertebroplasty in osteoporotic vertebral fractures. Biomed Res Int. 2014;2014:934206. doi: 10.1155/2014/934206. Epub 2014 Mar 4.

 

Papanastassiou ID, Filis AK, Gerochristou MA, Vrionis FD. Controversial issues in kyphoplasty and vertebroplasty in malignant vertebral fractures. Cancer Control. 2014 Apr;21(2):151-7.

 

Filis AK, Aghayev KV, Doulgeris JJ, Gonzalez-Blohm SA, Vrionis FD. Spinal neoplastic instability: biomechanics and current management options. Cancer Control. 2014 Apr;21(2):144-50.

 

Papanastassiou ID, Filis A, Aghayev K, Kokkalis ZT, Gerochristou MA, Vrionis FD. Adverse prognostic factors and optimal intervention time for kyphoplasty/vertebroplasty in osteoporotic fractures. Biomed Res Int. 2014;2014:925683. doi: 10.1155/2014/925683. Epub 2014 Jan 19.

 

Abdulazim A, Filis A, Sadr-Eshkevari P, Schulte F, Sandu N, Schaller B. Postcraniotomy function of the temporal muscle in skull base surgery: technical note based on a preliminary study. ScientificWorldJournal. 2012;2012:427081

Schaller BJ, Filis A, Merten HA, Buchfelder M. Premature craniosynostosis - The role of skull base surgery in its correction. A surgical and radiologal experience of 172 operated infants/children. J Craniomaxillofac Surg. 2011 May 19

Schulte F, Filis A, Karageorgos N, Sandu N, Schaller B. Pain after craniotomy - really a problem? Arch Med Sci. 2010 Dec;6(6):827-8.

 

 

Sandu N, Cornelius J, Filis A, Nöthen C, Rasper J, Kulinsky VI, Schaller BJ; Trigemino-Cardiac-Reflex-Examination-Group (T.C.R.E.G.). Cerebral hemodynamic changes during the trigeminocardiac reflex: description of a new animal model protocol.

ScientificWorldJournal. 2010 Jul 20;10:1416-23

Moon K, Filis AK, Cohen AR. The birth and evolution of neuroscience through cadaveric dissection. Neurosurgery. 2010 Sep;67(3):799-809; discussion 809-10

Sandu N, Spiriev T, Lemaitre F, Filis A, Schaller B; Trigemino-Cardiac-Reflex-Examination-Group (T.C.R.E.G.). New molecular knowledge towards the trigemino-cardiac reflex as a cerebral oxygen-conserving reflex. ScientificWorldJournal. 2010 May 4;10:811-7

Nöthen C, Sandu N, Prabhakar H, Filis A, Arasho BD, Buchfelder M, Schaller BJ. Trigemino-cardiac reflex and antecedent transient ischemic attacks. Expert Rev Cardiovasc Ther. 2010 Apr;8(4):509-12

Filis AK, Moon K, Cohen AR. Synchronous ventriculoscopic and microsurgical resection of complex craniopharyngiomas. Pediatr Neurosurg. 2009;45(6):434-6. Epub 2010 Jan 26. Review.

Filis AK, Moon K, Cohen AR. Symptomatic Subdural Hygroma and Hydrocephalus following Chiari I Decompression. Pediatr Neurosurg. 2009;45(6):425-8. Epub 2009 Dec 24.

Moon K, Filis AK, Cohen AR. Mobile spinal ependymoma. J Neurosurg Pediatr. 2010 Jan;5(1):85-8.

Sandu N, Cornelius J, Filis A, Arasho B, Perez-Pinzon M, Schaller B. Ischemic tolerance in stroke treatment. Expert Rev Cardiovasc Ther. 2009 Oct;7(10):1255-61

 

Schaller B, Sandu N, Cornelius JF, Filis A. Comment on "Asystole due to trigemino-cardiac reflex: A rare complication of trans-sphenoidal surgery for pituitary adenoma". J Clin Neurosci. 2009 Dec;16(12):1709

Schaller B, Cornelius JF, Prabhakar H, Koerbel A, Gnanalingham K, Sandu N, Ottaviani G, Filis A, Buchfelder M; Trigemino-Cardiac Reflex Examination Group (TCREG). The trigemino-cardiac reflex: an update of the current knowledge. J Neurosurg Anesthesiol. 2009 Jul;21(3):187-95. Review.

Schaller B, Filis A, Sandu N, Buchfelder M; Trigemino-Cardiac-Reflex Examination Group (T.C.R.E.G.). Peripheral trigemino-cardiac reflex. Acta Neurochir (Wien). 2009 Dec;151(12):1727. Epub 2009 May 26

Schaller BJ, Sandu N, Cornelius JF, Filis A, Perez-Pinzon MA; Trigemino-Cardiac-Reflex-Examination-Group (T.C.R.E.G.). Oxygen-conserving implications of the trigemino-cardiac reflex in the brain: the molecular basis of neuroprotection? Mol Med. 2009 May-Jun;15(5-6):125-6

Schaller B, Sandu N, Filis A, Ottaviani G, Rasper J, Nöethen C, Buchfelder M; Trigemino-Cardiac-Reflex-Examination-Group (T.C.R.E.G.). Trigemino-cardiac reflex: the trigeminal depressor responses during skull base surgery. Clin Neurol Neurosurg. 2009 Feb;111(2):220. Epub 2008 Nov 8

Schaller B, Sandu N, Filis A, Buchfelder M. Peribulbar block or topical application of local anaesthesia combined for paediatric strabismus surgery. Anaesthesia. 2008 Oct;63(10):1142-3; author reply 1143-4

 

Schaller B, Sandu N, Filis A, Buchfelder M; Trigemino-Cardiac-Reflex-Examination-Group. Cardiovascular responses during percutaneous radiofrequency thermocoagulation therapy in primary trigeminal neuralgia: an explanation of the trigeminocardiac reflex?

J Neurosurg Anesthesiol. 2008 Oct;20(4):270

 

Schaller B, Filis A, Sandu N, Rasper J, Noethen C, Buchfelder M; Trigemino-Cardiac-Reflex-Examination-Group. Trigemino-cardiac reflex may be refractory to conventional management in adults. Acta Neurochir (Wien). 2008 Sep;150(9):929-30; author reply 931

Schaller B, Sandu N, Ottoviani G, Filis A, Noethen C, Buchfelder M; Trigemino-Cardiac-Reflex-Examination-Group. Transient asystole during endoscopic transsphenoidal surgery: an example of trigeminocardiac reflex. Pituitary. 2009;12(3):271-2.

Schaller BJ, Filis A, Buchfelder M. Trigemino-cardiac reflex in humans initiated by peripheral stimulation during neurosurgical skull-base operations. Its first description. Acta Neurochir (Wien). 2008 Jul;150(7):715-7; discussion 717-8.

Schaller B, Filis A, Buchfelder M; Trigemino-Cardiac-Reflex-Examination-Group. Trigeminocardiac reflex in embolization of intracranial dural arteriovenous fistula.AJNR Am J Neuroradiol. 2008 Aug;29(7):E55.

Schaller BJ, Rasper J, Filis A, Buchfelder M. Difference in functional outcome of ipsilateral tinnitus after intraoperative occurrence of the trigemino-cardiac reflex in surgery for vestibular schwannomas. Acta Neurochir (Wien). 2008 Feb;150(2):157-60. Epub 2007 Dec

Filis A, Schaller B, Buchfelder M. [Trigeminocardiac reflex in pituitary surgery. A prospective pilot study] Nervenarzt. 2008 Jun;79(6):669-75.

Schaller BJ, Weigel D, Filis A, Buchfelder M. Trigemino-cardiac reflex during transsphenoidal surgery for pituitary adenomas: methodological description of a prospective skull base study protocol. Brain Res. 2007 May 29;1149:69-75. Epub 2007 Jan 12.

Schaller BJ, Filis A, Buchfelder M. Detection and prevention of the trigeminocardiac reflex during skull base surgery. Acta Neurochir (Wien). 2007 Mar;149(3):331.